BDBM50080017 (+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol]::(+/-)-ifenprodil::-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-((1S,2R)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol::4-[(1S,2R)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol::CHEMBL113830::ifenprodil

SMILES C[C@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=UYNVMODNBIQBMV-IIBYNOLFSA-N

Data  18 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080017   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50080017((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]-unlike-ifenprodil from recombinant human GluN2B expressed in L-M(TK-) cell membranes by competitive receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50080017((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50080017((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  698nMAssay Description:Antagonist activity at human GluN2B expressed in Xenopus laevis oocytes assessed as reduction in glutamate and glycine stimulated ion flux by two-ele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed